Tropicamide 0.5% , 1% Suppliers & Bulk Manufacturers

Available Forms: Eye Drops

Available Strengths: 0.5% , 1%

Reference Brands: Mydriacyl (USA/EU)

Category: Opthalmology

Tropicamide 0.5% and 1% eye drops, a short-acting antimuscarinic for pupil dilation and cycloplegia in eye examinations, for hospital eye units, optometry suppliers, distributors and importers.

Product Description:

Tropicamide is a short-acting antimuscarinic eye drop. It blocks acetylcholine at the iris sphincter and ciliary muscle, so the pupil widens (mydriasis) and focusing relaxes for a while (cycloplegia). This page covers 0.5% and 1% solutions. The 0.5% strength is common for dilating the pupil before fundus examination, while 1% gives stronger cycloplegia for refraction. Quick onset and effects that usually wear off within several hours make it the routine choice for dilated examinations.

Optometrists and ophthalmologists use it for dilated examinations, retinal screening, and before cataract and retinal procedures, often with phenylephrine for fuller dilation. One or two drops are instilled, and examination follows once the pupil has dilated, typically within half an hour. Patients should not drive until blurred vision and glare clear. Dilation can trigger angle-closure in narrow-angle eyes. Infants are more sensitive to systemic effects, and pressing the inner corner of the eye after instillation limits absorption.

Sourcing notes. Tropicamide drops are prescription-only or limited to eye-care professionals in most markets, and some regulators have tightened control after reported misuse, so check local rules. Multi-dose bottles usually contain benzalkonium chloride and carry an in-use period after opening; preservative-free single-dose units suit busy clinics. Registration needs a CTD or ACTD dossier with sterility and container closure data. Ask for stability data covering the target climate, a batch CoA with sterility and pH, sterile ophthalmic GMP and a CoPP. Specify strength, fill and preservative status.