Omidenepag Isopropyl 0.002% Suppliers & Bulk Manufacturers

Available Forms: Eye Drops

Available Strengths: 0.002%

Reference Brands: Eybelis

Category: Opthalmology

Omidenepag Isopropyl is a Opthalmology product available as Eye Drops in strengths 0.002%. It corresponds to the reference brand Eybelis. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Omidenepag isopropyl ophthalmic solution 0.002% (EYBELIS®) is a selective prostaglandin E2 receptor subtype 2 (EP2) agonist with a unique non-prostaglandin chemical structure. It has been developed for the treatment of glaucoma and ocular hypertension, conditions characterized by elevated intraocular pressure that can lead to progressive optic nerve damage and vision loss if left untreated. The product is the result of a collaborative development effort between Ube Industries and Santen Pharmaceutical.

Unlike conventional prostaglandin analogs, omidenepag isopropyl acts selectively on the EP2 receptor, promoting increased aqueous humor outflow through both trabecular and uveoscleral pathways. This distinct mechanism of action offers effective intraocular pressure reduction while providing a differentiated therapeutic profile. Omidenepag isopropyl is administered as a once-daily ophthalmic solution, supporting patient compliance in long-term glaucoma management.

Based on positive outcomes from phase III clinical trials demonstrating its efficacy and safety, omidenepag isopropyl ophthalmic solution 0.002% received regulatory approval in Japan in September 2018. This approval marked the first global authorization for this novel EP2 receptor agonist in glaucoma and ocular hypertension treatment, representing an important advancement in ophthalmic therapeutic options.