Treosulfan 1 g, 5 g Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 1 g, 5 g

Reference Brands: Trecondi (EU/UK)

Category: Oncology Cancer Care

Treosulfan is a Oncology Cancer Care product available as Injection in strengths 1 g, 5 g. It corresponds to the reference brand Trecondi (EU/UK). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Treosulfan is an alkylating antineoplastic agent used as part of conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT). It is administered to patients before bone marrow transplantation to eliminate existing bone marrow cells and create space for donor stem cells to engraft and produce healthy blood cells. Treosulfan is commonly marketed under the brand name Trecondi in regulated markets.

Treosulfan is used in combination with fludarabine in both adult and pediatric patients, including children from one month of age, for the treatment of hematological malignancies such as blood cancers, as well as in adults with certain severe non-malignant disorders that require stem cell transplantation. It belongs to the class of alkylating agents and exerts its therapeutic effect through cytotoxic activity on rapidly dividing cells.

After administration, treosulfan is converted in the body into active epoxide compounds. These metabolites bind to cellular DNA during cell division, causing DNA damage and leading to cell death, particularly in rapidly proliferating tissues such as bone marrow. Due to its predictable pharmacokinetics and controlled toxicity profile, treosulfan plays an important role in modern transplant conditioning protocols under specialist medical supervision.