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Lomustine bulk supplier for pharma manufacturers

Lomustine 10 mg, 40 mg, 100 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 10 mg, 40 mg, 100 mg

Reference Brands: Gleostine (USA)

Category: Oncology Cancer Care

Lomustine is a Oncology Cancer Care product available as Capsules in strengths 10 mg, 40 mg, 100 mg. It corresponds to the reference brand Gleostine (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Lomustine is a nitrosourea alkylating agent with potent antineoplastic activity, widely used in chemotherapy protocols for the treatment of various malignancies. It works by alkylating and crosslinking DNA, which leads to inhibition of DNA and RNA synthesis and ultimately results in cancer cell death. In addition, lomustine carbamoylates DNA and cellular proteins, further disrupting RNA processing and impairing tumor cell replication.

Lomustine is a highly lipophilic compound, allowing it to effectively cross the blood–brain barrier. This unique pharmacokinetic property makes it particularly valuable in the treatment of primary and metastatic brain tumors, where many anticancer agents have limited penetration. It is most commonly used in the management of brain tumors and is also employed as a second-line treatment option for Hodgkin lymphoma, especially in cases where standard therapies have failed.

Internationally known by the abbreviation CCNU, lomustine was originally marketed under the brand name CeeNU and is currently available as Gleostine in regulated markets. Due to its strong cytotoxic activity, lomustine is administered under strict medical supervision as part of carefully monitored chemotherapy regimens.

Lomustine — third party manufacturing & bulk supply

Lomustine 10 mg, 40 mg, 100 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Lomustine is supplied as Capsules — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Lomustine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Lomustine is used to treat brain tumors, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and other cancers, either alone or in combination with other anticancer medicines.

Lomustine is made from the active pharmaceutical ingredient lomustine, a synthetic nitrosourea compound with alkylating properties.

The trade names of Lomustine are Gleostine and CeeNU.

Gleostine is manufactured and marketed by NextSource Biotechnology LLC, while generic lomustine is produced by multiple oncology-focused pharmaceutical manufacturers worldwide.

The generic name is lomustine.

The brand names are Gleostine and CeeNU.

Lomustine is manufactured in GMP-approved facilities across the USA, EU, and other regulated markets for oncology use.

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