Idarubicin Hydrochloride bulk supplier for pharma manufacturers

Idarubicin Hydrochloride 5 mg/5 mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 5 mg/5 mL

Reference Brands: Idamycin (USA)

Idarubicin Hydrochloride is a Oncology Cancer Care product available as Injection in strengths 5 mg/5 mL. It corresponds to the reference brand Idamycin (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Idarubicin hydrochloride is an anthracycline antileukemic agent widely used in combination chemotherapy regimens for the treatment of acute myeloid leukemia (AML) in adult patients. It is commonly administered alongside other anticancer drugs during induction therapy under strict oncologist supervision. In addition to its approved use in AML, idarubicin hydrochloride is also being studied for its potential role in the treatment of other malignancies.

Pharmacologically, idarubicin hydrochloride works by intercalating into DNA and inhibiting the activity of topoisomerase II, an essential enzyme involved in DNA replication, transcription, and repair. By blocking this enzyme, the drug prevents proper DNA unwinding and cell division, ultimately leading to cancer cell death. The compound is a structural analog of daunorubicin; however, the absence of a methoxy group increases its lipophilicity, allowing for enhanced cellular uptake and greater antitumor activity.

Like other anthracyclines, idarubicin hydrochloride also affects chromatin structure by inducing histone eviction, further disrupting cancer cell survival mechanisms. Due to its potent cytotoxic effects, its use requires careful dosing and monitoring in specialized oncology settings.

Idarubicin Hydrochloride — third party manufacturing & bulk supply

Idarubicin Hydrochloride 5 mg/5 mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Idarubicin Hydrochloride is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Idarubicin Hydrochloride listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Idarubicin hydrochloride is used primarily in the treatment of acute myeloid leukemia (AML), often in combination with other anticancer drugs as part of induction therapy.

Idarubicin hydrochloride is a semi-synthetic anthracycline antibiotic derived from daunorubicin, chemically modified to enhance lipophilicity and cellular uptake.

The most recognized trade name is Idamycin PFS, while in many regions it is supplied under the generic name Idarubicin Hydrochloride Injection.

Idamycin PFS was originally developed and marketed by Pfizer. Today, idarubicin hydrochloride is manufactured by multiple generic pharmaceutical companies worldwide.

The complete generic name is idarubicin hydrochloride.

A commonly known brand name is Idamycin PFS, along with various generic-branded versions in different countries.

Idarubicin hydrochloride is manufactured in several countries, including the USA, EU member states, India, and other GMP-approved pharmaceutical manufacturing hubs, depending on the supplier.