Pentostatin 10 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 10 mg

Reference Brands: Nipent (USA/EU)

Category: Oncology Cancer Care

Pentostatin is a Oncology Cancer Care product available as Injection in strengths 10 mg. It corresponds to the reference brand Nipent (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Pentostatin is a chemotherapeutic agent used primarily in the treatment of hematologic malignancies, most notably hairy cell leukemia. It is administered by intravenous infusion, typically once every two weeks over a treatment period of three to six months, depending on patient response and clinical protocol. Pentostatin works by inhibiting the enzyme adenosine deaminase, which leads to the accumulation of toxic metabolites in malignant lymphocytes and results in cancer cell death.

In addition to its approved use in hairy cell leukemia, pentostatin has been utilized in the treatment of other lymphoid disorders, including relapsed chronic lymphocytic leukemia (CLL) and T-cell prolymphocytic leukemia. It has also shown clinical benefit in patients with steroid-refractory acute and chronic graft-versus-host disease, particularly in cases where standard therapies have failed.

Pentostatin is marketed under the brand name Nipent and is supplied as a lyophilized powder for intravenous infusion. As a chemotherapy agent, its use requires careful patient monitoring due to potential adverse effects such as immunosuppression, infections, and hematologic toxicity. When administered under appropriate clinical supervision, pentostatin remains an effective and well-established option in the management of select leukemias and refractory immune-mediated conditions.