Topotecan Injection 2.5 mg, 4 mg/4 mL Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 2.5 mg, 4 mg/4 mL
Reference Brands: Topotel (USA), Calbitin (USA/EU)
Category: Oncology Cancer Care
Topotecan is used in the treatment of ovarian cancer.
Product Description:
Topotecan, marketed under the brand name Hycamtin and other regional brands, is a chemotherapeutic agent belonging to the class of topoisomerase inhibitors. It is a synthetic, water-soluble analog of the natural compound camptothecin and is used in its hydrochloride salt form for medical administration. By inhibiting the enzyme topoisomerase I, Topotecan interferes with DNA replication in rapidly dividing cancer cells, leading to cell death and slowing the progression of tumors.
Topotecan is primarily used for the treatment of ovarian cancer and small cell lung cancer, and it is sometimes employed for other malignancies based on clinical judgment. It is administered intravenously as an injection or, in certain cases, orally in capsule form. Due to its potent cytotoxic effects, careful dosing, patient monitoring, and management of side effects such as myelosuppression, nausea, and hair loss are essential during therapy.
The medication plays a critical role in modern oncology by targeting rapidly proliferating cancer cells while minimizing effects on normal tissues. When used under specialist supervision, Topotecan can help control disease progression, improve patient outcomes, and provide a valuable treatment option for patients with challenging cancers.
Topotecan Injection — third party manufacturing & bulk supply
Topotecan Injection 2.5 mg, 4 mg/4 mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Topotecan Injection listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Topotecan Injection →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Topotecan is a chemotherapy medication used to treat certain types of cancer, including small cell lung cancer (SCLC) and ovarian cancer. It works by slowing or stopping the growth of cancer cells.
Topotecan is a synthetic camptothecin derivative that inhibits the enzyme topoisomerase I. By blocking this enzyme, it prevents DNA replication in rapidly dividing cancer cells, leading to cell death.
Topotecan is marketed under trade names such as Hycamtin.
Topotecan (Hycamtin) is manufactured by GlaxoSmithKline and several generic pharmaceutical companies worldwide.
The complete generic name is topotecan hydrochloride.
The brand name is Hycamtin.
Topotecan is manufactured in the USA, EU countries, and India, depending on the brand and generic manufacturer.
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