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Topotecan Injection bulk supplier for pharma manufacturers

Topotecan Injection Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 2.5 mg, 4 mg/4 mL

Reference Brands: Topotel (USA), Calbitin (USA/EU)

Category: Oncology Cancer Care

Topotecan is used in the treatment of ovarian cancer. Topotecan Injection is available in Injection and strengths such as 2.5 mg, 4 mg/4 mL. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Topotecan Injection is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Topotecan Injection can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Topotecan, marketed under the brand name Hycamtin and other regional brands, is a chemotherapeutic agent belonging to the class of topoisomerase inhibitors. It is a synthetic, water-soluble analog of the natural compound camptothecin and is used in its hydrochloride salt form for medical administration. By inhibiting the enzyme topoisomerase I, Topotecan interferes with DNA replication in rapidly dividing cancer cells, leading to cell death and slowing the progression of tumors.

Topotecan is primarily used for the treatment of ovarian cancer and small cell lung cancer, and it is sometimes employed for other malignancies based on clinical judgment. It is administered intravenously as an injection or, in certain cases, orally in capsule form. Due to its potent cytotoxic effects, careful dosing, patient monitoring, and management of side effects such as myelosuppression, nausea, and hair loss are essential during therapy.

The medication plays a critical role in modern oncology by targeting rapidly proliferating cancer cells while minimizing effects on normal tissues. When used under specialist supervision, Topotecan can help control disease progression, improve patient outcomes, and provide a valuable treatment option for patients with challenging cancers.

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Frequently Asked Questions

Topotecan is a chemotherapy medication used to treat certain types of cancer, including small cell lung cancer (SCLC) and ovarian cancer. It works by slowing or stopping the growth of cancer cells.

Topotecan is a synthetic camptothecin derivative that inhibits the enzyme topoisomerase I. By blocking this enzyme, it prevents DNA replication in rapidly dividing cancer cells, leading to cell death.

Topotecan is marketed under trade names such as Hycamtin.

Topotecan (Hycamtin) is manufactured by GlaxoSmithKline and several generic pharmaceutical companies worldwide.

The complete generic name is topotecan hydrochloride.

The brand name is Hycamtin.

Topotecan is manufactured in the USA, EU countries, and India, depending on the brand and generic manufacturer.

Yes, Topotecan Injection is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Topotecan Injection is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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