Pregabalin / Nortriptyline Tablet 75mg + 10mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 75mg + 10mg
Reference Brands: Various Indian Brand
Category: Antipsychotropic Drugs
Pregabalin + Nortriptyline is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
Product Description:
Pregabalin and nortriptyline hydrochloride is a combination medication widely used for the management of chronic neuropathic pain, a condition caused by nerve damage or dysfunction. It is commonly prescribed for patients suffering from diabetic neuropathy, post-herpetic neuralgia, spinal cord injury-related pain, and other nerve-related disorders. This combination is especially beneficial when pain is persistent and not adequately controlled by single-drug therapy.
The formulation works through a dual mechanism of action. Pregabalin, an anticonvulsant, helps regulate calcium channel activity in nerve cells, thereby reducing the transmission of pain signals to the brain. Nortriptyline hydrochloride, a tricyclic antidepressant, enhances the levels of neurotransmitters such as norepinephrine, which play a key role in modulating pain perception and improving mood.
Together, these components provide synergistic relief by targeting both the physical and neurological aspects of pain. In addition to reducing pain intensity, the combination may also improve sleep quality and overall quality of life in patients with chronic conditions. It is generally prescribed under medical supervision to ensure safe and effective use.
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Frequently Asked Questions
This combination is primarily used for the management of neuropathic pain conditions such as diabetic neuropathy, post-herpetic neuralgia, and nerve-related chronic pain. It also helps in reducing associated symptoms like burning, tingling, and sleep disturbances.
It is made from pregabalin, which modulates calcium channel activity to reduce nerve pain signals, and nortriptyline hydrochloride, a tricyclic antidepressant that enhances neurotransmitters like norepinephrine to help relieve pain and improve mood.
Common trade names include Nervigesic NT, Preganerve NT, Pregaba NT, Nortryptomer-P, and several other region-specific branded generics.
This combination is manufactured by multiple pharmaceutical companies, especially in India and emerging markets, including companies like Cipla, Sun Pharma, Intas, and others.
The generic names are pregabalin and nortriptyline hydrochloride.
Brand names include Nervigesic NT, Preganerve NT, Pregaba NT, Nortryptomer-P, and other local branded generics depending on the manufacturer.
It is primarily manufactured in India and exported to various regions including Asia, Africa, and some LATAM markets, with limited availability in regulated markets like the USA and EU as a fixed-dose combination.
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