Ketoconazole Powder 2% Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: 2%

Reference Brands: Generic formulations marketed under different names

Category: Anti-fungal

Keto Dusting Powder is an antifungal medicine. It is used to treat skin infections caused by fungi. These include athlete's foot, ringworm, vaginal thrush, and sweat rash. It works by killing and stopping the growth of fungi, thereby clearing the infection and relieving the symptoms.

Product Description:

Ketoconazole is an imidazole antifungal that blocks the fungal enzyme converting lanosterol to ergosterol, destabilising the cell membrane. As a dusting powder the drug is carried in an absorbent base, so the product both treats the infection and addresses the moisture that allowed it — dermatophytes and Candida need warm, damp skin, and drying the area is half the treatment in body folds and between toes.

It is used for tinea pedis, tinea cruris, cutaneous candidiasis and pityriasis versicolor, and as maintenance after a cream has cleared an infection, particularly in humid climates where recurrence is the norm. Topical ketoconazole is well tolerated; local irritation and itching are the usual complaints. This is quite different from oral ketoconazole, whose systemic use has been severely restricted in most markets because of hepatotoxicity and adrenal suppression — a restriction that does not apply to topical use, where absorption is negligible.

Sourcing notes. Off patent and widely available, with the shampoo and cream forms carrying larger volumes than the powder. The powder base — talc or an alternative — is a live commercial question in several markets. Regulatory classification differs: prescription in some markets, over the counter in others.