Pentoxifylline 400 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 400 mg

Reference Brands: Trental (USA/EU)

Category: Heart Disorder

Pentoxifylline is a Heart Disorder product available as Tablets in strengths 400 mg. It corresponds to the reference brand Trental (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Pentoxifylline is a xanthine derivative widely used in the management of peripheral vascular disease and other circulatory disorders. It acts as a phosphodiesterase inhibitor (PDEi), improving blood flow by reducing blood viscosity and enhancing red blood cell flexibility, thereby facilitating better microcirculation in ischemic tissues. By modulating blood rheology, pentoxifylline helps relieve symptoms of intermittent claudication and supports overall vascular health.

Pentoxifylline is administered orally, typically in tablet form, and is indicated for patients with peripheral artery disease, chronic occlusive arterial disease, or other conditions where improved blood flow can benefit tissue oxygenation. It has also been explored for off-label uses in vascular complications and microvascular disorders, though clinicians must carefully assess its suitability for individual patients.

Given its pharmacological complexity, pentoxifylline requires careful monitoring for adverse effects and potential drug interactions. Common side effects include gastrointestinal disturbances, dizziness, and headache, while severe reactions are rare. Its pharmacokinetics, dosing regimen, and patient-specific factors must be considered to ensure safety and efficacy. Pentoxifylline remains an important therapeutic option in cardiovascular care, offering targeted improvement of circulation and support for patients with vascular insufficiency.