Moexipril Hydrochloride 7.5 mg, 15 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 7.5 mg, 15 mg

Reference Brands: Univasc (USA)

Category: Heart Disorder

Moexipril Hydrochloride is a Heart Disorder product available as Tablets in strengths 7.5 mg, 15 mg. It corresponds to the reference brand Univasc (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Moexipril is an angiotensin-converting enzyme (ACE) inhibitor that has been used in the management of hypertension and congestive heart failure. It may be administered as monotherapy or in combination with other antihypertensive agents, including diuretics, to achieve optimal blood pressure control. By reducing systemic vascular resistance, moexipril helps improve blood flow and decreases the workload on the heart.

The primary mechanism of action of moexipril involves inhibition of the angiotensin-converting enzyme, which prevents the conversion of angiotensin I into angiotensin II. Since angiotensin II is a potent vasoconstrictor, its reduction leads to relaxation of blood vessels and effective lowering of blood pressure. This mechanism plays a key role in controlling hypertension within the vasculature and improving cardiovascular hemodynamics.

In addition to its antihypertensive effects, moexipril has demonstrated cardioprotective properties. Preclinical studies have shown that administration of moexipril prior to myocardial infarction resulted in a reduction in infarct size, indicating protective effects on heart tissue. These benefits are attributed to a combination of angiotensin II inhibition and increased bradykinin activity. Elevated bradykinin levels stimulate the production of prostaglandin E2 and nitric oxide, leading to vasodilation and antiproliferative effects, which further support cardiovascular protection.