Methylnaltrexone Bromide 12 mg/mL , 8 mg/mL , 450 mg Suppliers & Bulk Manufacturers

Available Forms: Tablet / Injection

Available Strengths: 12 mg/mL , 8 mg/mL , 450 mg

Reference Brands: Relistor (USA)

Category: Gastrointestinal Drugs

Methylnaltrexone Bromide is a Gastrointestinal Drugs product available as Tablet / Injection in strengths 12 mg/mL , 8 mg/mL , 450 mg. It corresponds to the reference brand Relistor (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Methylnaltrexone bromide is a peripherally acting mu-opioid receptor antagonist used to relieve constipation caused by opioid medications, commonly referred to as opioid-induced constipation (OIC). It is marketed under the brand name Relistor and is indicated for adult patients experiencing constipation due to opioid use for chronic pain, including pain associated with cancer, cancer treatment, or other advanced illnesses.

This medication works by selectively binding to opioid receptors in the gastrointestinal tract without crossing the blood-brain barrier, which allows it to block the constipating effects of opioids while preserving their pain-relieving properties. Methylnaltrexone bromide can be administered subcutaneously for rapid relief or orally for chronic management, depending on the patient’s condition and treatment plan.

By targeting peripheral opioid receptors, methylnaltrexone bromide effectively restores bowel function and provides relief from constipation without compromising analgesia. Its mechanism and safety profile make it a valuable option for patients who require long-term opioid therapy and need to maintain gastrointestinal regularity under medical supervision.