Methoxsalen 10 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 10 mg

Reference Brands: Oxsoralen (USA/EU)

Category: Derma Drugs

Methoxsalen is a psoralen that — when combined with UVA light therapy (PUVA) — helps treat skin disorders by modifying how skin cells respond to ultraviolet light. It is used for conditions such as psoriasis, vitiligo, and certain skin lymphomas.

Product Description:

Methoxsalen, also known as Xanthotoxin or 8-methoxypsoralen, is a photosensitizing medication primarily used in combination with ultraviolet A (UVA) light therapy to treat a range of skin conditions, including psoriasis, eczema, vitiligo, and certain cutaneous lymphomas. Marketed under brand names such as Oxsoralen and Melanocyl, methoxsalen works by modifying the way skin cells respond to UVA radiation, helping to reduce abnormal cell proliferation and restore pigmentation in affected areas.

Methoxsalen belongs to the furanocoumarin class of organic compounds, which are naturally occurring molecules composed of coumarin fused with a furan ring. Its unique chemical structure allows it to intercalate into DNA and, upon activation by UVA light, form cross-links that slow the growth of overactive skin cells. The therapy, commonly known as PUVA (psoralen + UVA), is carefully dosed based on individual patient sensitivity, historically assessed using the Fitzpatrick skin type scale to minimize phototoxicity.

Methoxsalen can be administered orally, topically, or via injection, depending on the condition being treated and the treatment protocol. By combining methoxsalen with controlled UVA exposure, clinicians can effectively manage chronic dermatologic disorders, improve skin appearance, and provide long-term disease control.