Magnesium Sulfate 50% w/w Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 50% w/w

Reference Brands:

Category: Women's Health

Magnesium sulfate injection is used to treat hypomagnesemia (low levels of magnesium in your blood). Magnesium sulfate injection is also used to prevent seizures in pregnant women with conditions such as pre-eclampsia, eclampsia, or toxemia of pregnancy.

Product Description:

Magnesium sulfate injection supplies magnesium, a cation that blocks NMDA receptors, stabilises excitable membranes, antagonises calcium at nerve terminals and relaxes smooth muscle. Those properties give it several unrelated uses across acute care.

Its most important use is in obstetrics: it is the treatment of choice for preventing and controlling eclamptic seizures in severe pre-eclampsia, where large trials showed it more than halved the risk of eclampsia and outperformed both diazepam and phenytoin. It is also given before preterm birth for fetal neuroprotection, reducing cerebral palsy. Beyond obstetrics it treats hypomagnesaemia, torsades de pointes, and severe asthma. Dosing is by gram, given as a loading dose then infusion, with monitoring of tendon reflexes, respiratory rate and urine output, since toxicity progresses from loss of reflexes to respiratory depression and cardiac arrest. Calcium gluconate is the antidote and must be immediately available.

Sourcing notes. An essential medicine bought largely through public and programme procurement. Concentration confusion is a documented cause of serious obstetric error, so labelling should state grams per ampoule as well as percentage. Ampoule volume and total grams per unit belong on every quotation.