Lone Sulbactam 1g /2g Suppliers & Bulk Manufacturers

Available Forms: injection

Available Strengths: 1g /2g

Reference Brands:

Category: Critical Care

Antibiotic

Product Description:

Sulbactam is a beta-lactamase inhibitor: a penicillin-like molecule with almost no antibacterial activity of its own that binds and disables the enzymes bacteria use to destroy beta-lactam antibiotics. It is normally supplied combined with ampicillin or cefoperazone, where it restores the partner antibiotic's activity against resistant organisms.

Sulbactam has one genuine exception to its lack of intrinsic activity: it binds penicillin-binding proteins in Acinetobacter baumannii and kills it directly. That makes it one of the few options against carbapenem-resistant Acinetobacter, where it is given at high doses, usually alongside another active agent, and it is the basis of a newer combination pairing sulbactam with a second-generation beta-lactamase inhibitor. Single-agent sulbactam vials let clinicians add sulbactam to a separately chosen beta-lactam, or push the sulbactam dose above what a fixed combination allows. It is well tolerated; rash, diarrhoea and injection-site pain are the usual effects, and the dose is reduced in renal impairment.

Sourcing notes. Standalone sulbactam vials are registered in India and some other markets but not widely in regulated markets, where it is sold only in combination. Confirm registration in the destination country before quoting. Vials are sterile lyophilised powder.