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Lidocaine hydrochloride / Epinephrine bulk supplier for pharma manufacturers

Lidocaine Hydrochloride / Epinephrine 2%+1:50,000, 2%+1:80,000 Suppliers & Bulk Manufacturers

Available Forms: Dental cartridge

Available Strengths: 2%+1:50,000, 2%+1:80,000

Reference Brands: Xylocaine (USA/EU), Lignox (India), Lignospan (LATAM)

Category: Dental / Oral Health

Lidocaine Hydrochloride / Epinephrine is a Dental / Oral Health product available as Dental cartridge in strengths 2%+1:50,000, 2%+1:80,000. It corresponds to the reference brands Xylocaine (USA/EU), Lignox (India), Lignospan (LATAM). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Lidocaine hydrochloride and epinephrine injection is a sterile, widely used local anesthetic combination designed to provide effective numbness during medical, dental, and minor surgical procedures. It combines lidocaine, an amide-type local anesthetic, with epinephrine, a vasoconstrictor that enhances the overall efficacy of the formulation. Lidocaine works by blocking nerve signal transmission at the site of administration, thereby preventing pain sensation, while epinephrine constricts blood vessels, helping to prolong the duration of anesthesia and minimize bleeding during procedures.

This combination is particularly valued for its rapid onset of action and reliable depth of anesthesia, making it suitable for procedures such as tooth extractions, suturing, biopsies, and minor surgical interventions. The addition of epinephrine also helps reduce systemic absorption of lidocaine, improving safety and allowing for better control of the anesthetic effect. Available in various strengths and commonly supplied in pre-filled cartridges or vials, it is widely used by healthcare professionals across clinical settings. Due to its proven efficacy, safety profile, and versatility, lidocaine with epinephrine remains one of the most commonly used local anesthetic combinations worldwide.

Lidocaine Hydrochloride / Epinephrine — third party manufacturing & bulk supply

Lidocaine Hydrochloride / Epinephrine 2%+1:50,000, 2%+1:80,000 is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Lidocaine Hydrochloride / Epinephrine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Lidocaine hydrochloride + epinephrine injection is used to provide local anesthesia during medical and dental procedures. It helps numb the targeted area and prevents pain during procedures such as minor surgeries, dental treatments, and other interventions.

It is made from lidocaine hydrochloride, which blocks nerve signal transmission to produce anesthesia, combined with epinephrine, which constricts blood vessels to prolong the anesthetic effect and reduce bleeding.

Trade names include Xylocaine, Lignospan, Cook-Waite Lidocaine, Dentocan, and Lignox depending on the region.

It is manufactured by several pharmaceutical companies such as Dentsply, Septodont, AstraZeneca (Xylocaine), and other global generic manufacturers.

The generic name is lidocaine hydrochloride + epinephrine injection.

Brand names include Xylocaine, Lignospan, Cook-Waite Lidocaine, Dentocan, and Lignox.

It is manufactured in multiple countries including the USA, France, Germany, India, and other regions with established pharmaceutical manufacturing facilities.

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