Lactoferrin and Disodium Guanosine 5-Monophosphate Tablets Suppliers & Bulk Manufacturers

Available Forms: Tablet

Available Strengths: Lactoferrin-100 mg,Disodium Guanosine 5-monophosphate-10 mg

Reference Brands:

Category: Nephrology

renal nutrition

Product Description:

This tablet combines lactoferrin with disodium guanosine 5'-monophosphate. Lactoferrin is an iron-binding glycoprotein found in milk and mucosal secretions. It binds iron tightly, carries it across the intestinal wall through its own receptor-mediated route rather than the transporter that ferrous salts use, and has anti-inflammatory activity that may lower hepcidin, the hormone that blocks iron absorption and traps iron in stores.

That last point is why it is of interest in kidney disease. Inflammation in chronic kidney disease raises hepcidin, which is a large part of why oral ferrous salts often fail in these patients and why intravenous iron is used so widely. Trials of lactoferrin, mostly small and largely in pregnancy rather than kidney disease, report haemoglobin improvements comparable to ferrous sulphate with fewer gastrointestinal complaints. The evidence in renal anaemia specifically is thin, and it does not replace assessment of iron status, erythropoietin therapy or intravenous iron where those are indicated.

Sourcing notes. Bovine lactoferrin quality varies with purity, iron saturation and heat damage in processing; all three belong in the specification. People with cow's milk protein allergy should avoid it. Classification ranges from food supplement to registered medicine depending on the claim made about anaemia.