L-Isoleucine,L-Leucine,L-Valine,ZINC Citrate Sachet Suppliers & Bulk Manufacturers

Available Forms: Sachet

Available Strengths: -

Reference Brands:

Category: Nutraceuticals

Sachet contains branched chain amino acids L-leucine 2.34g, L-isoleucine 1.20g, L-valine 1.56g, and Zinc citrate 24mg. It improves the quality of life and nutritional status in patients with liver disorders such as nonalcoholic fatty liver disease (a condition in which too much fat is stored in liver cells), hepatic encephalopathy (an altered level of consciousness due to liver failure), and end-stage liver disease (a condition in which scar tissue replaces healthy liver tissue).

Product Description:

This sachet supplies the three branched-chain amino acids — L-leucine, L-isoleucine and L-valine — with zinc. Unlike other amino acids, BCAAs are metabolised mainly in muscle rather than the liver. In cirrhosis, blood BCAA levels fall while aromatic amino acids rise, and that imbalance is thought to contribute to hepatic encephalopathy and muscle wasting. Supplementing BCAAs aims to correct the balance and support muscle and nutritional status. Zinc deficiency is also common in cirrhosis and affects ammonia metabolism.

BCAA granules have been used for decades in Japan in decompensated cirrhosis to improve nutritional status and reduce complications. A Cochrane review found that BCAAs improved symptoms of hepatic encephalopathy but did not reduce mortality. They are an addition to, not a replacement for, lactulose, rifaximin and nutritional care. Taken as a late-evening snack, they may help reduce overnight muscle breakdown. They are well tolerated, although the taste can affect adherence.

Sourcing notes. Registered as a medicine in Japan and some other markets, but as a food for special medical purposes or a supplement elsewhere, so classification depends on the claims. The leucine-to-isoleucine-to-valine ratio should match the evidence-based formula, and amino acid grade and origin are key specifications.