Isavuconazonium Sulfate bulk supplier for pharma manufacturers

Isavuconazonium Sulfate 100 mg , 186 mg, 372 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules / Injection

Available Strengths: 100 mg , 186 mg, 372 mg

Reference Brands: Cresemba (USA)

Isavuconazonium Sulfate is a Anti-fungal product available as Capsules / Injection in strengths 100 mg , 186 mg, 372 mg. It corresponds to the reference brand Cresemba (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Isavuconazonium sulfate is the sulfate ester form of isavuconazonium, a water-soluble prodrug of the triazole antifungal agent isavuconazole. Marketed under the brand name Cresemba, it is a systemic antifungal medication with broad-spectrum activity and is indicated for the treatment of invasive aspergillosis and invasive mucormycosis. It is administered either orally or intravenously under medical supervision.

Following administration, isavuconazonium sulfate is rapidly hydrolyzed by plasma esterases to release the active moiety, isavuconazole. Isavuconazole exerts its antifungal effect by binding to and inhibiting the fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase (CYP51), which is essential for the conversion of lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane.

Inhibition of ergosterol synthesis results in disruption of fungal cell membrane integrity, increased membrane permeability, and leakage of essential intracellular components. This leads to fungal cell lysis and death. Isavuconazonium sulfate provides an effective therapeutic option for serious, life-threatening invasive fungal infections.

Isavuconazonium Sulfate — third party manufacturing & bulk supply

Isavuconazonium Sulfate 100 mg , 186 mg, 372 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Isavuconazonium Sulfate is supplied as Capsules / Injection — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Isavuconazonium Sulfate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Isavuconazonium sulfate is used for the treatment of invasive fungal infections, particularly invasive aspergillosis and invasive mucormycosis, in adult patients who require systemic antifungal therapy.

Isavuconazonium sulfate is a water-soluble prodrug that is rapidly converted in the body to isavuconazole, a broad-spectrum triazole antifungal agent that inhibits fungal cell membrane synthesis.

Isavuconazonium sulfate is marketed under the trade name Cresemba.

Isavuconazonium sulfate (Cresemba) is manufactured by Astellas Pharma, depending on regional regulatory approvals.

The generic name of the product is isavuconazonium sulfate.

A commonly recognized brand name of isavuconazonium sulfate is Cresemba.

Isavuconazonium sulfate is manufactured in various countries including the USA, EU member states, and other regions, depending on the approved manufacturing site and market authorization.