Isavuconazonium Sulfate 100 mg , 186 mg, 372 mg Suppliers & Bulk Manufacturers
Available Forms: Capsules / Injection
Available Strengths: 100 mg , 186 mg, 372 mg
Reference Brands: Cresemba (USA)
Category: Anti-fungal
Isavuconazonium Sulfate is a Anti-fungal product available as Capsules / Injection in strengths 100 mg , 186 mg, 372 mg. It corresponds to the reference brand Cresemba (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Isavuconazonium sulfate is the sulfate ester form of isavuconazonium, a water-soluble prodrug of the triazole antifungal agent isavuconazole. Marketed under the brand name Cresemba, it is a systemic antifungal medication with broad-spectrum activity and is indicated for the treatment of invasive aspergillosis and invasive mucormycosis. It is administered either orally or intravenously under medical supervision.
Following administration, isavuconazonium sulfate is rapidly hydrolyzed by plasma esterases to release the active moiety, isavuconazole. Isavuconazole exerts its antifungal effect by binding to and inhibiting the fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase (CYP51), which is essential for the conversion of lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane.
Inhibition of ergosterol synthesis results in disruption of fungal cell membrane integrity, increased membrane permeability, and leakage of essential intracellular components. This leads to fungal cell lysis and death. Isavuconazonium sulfate provides an effective therapeutic option for serious, life-threatening invasive fungal infections.
Isavuconazonium Sulfate — third party manufacturing & bulk supply
Isavuconazonium Sulfate 100 mg , 186 mg, 372 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Isavuconazonium Sulfate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Isavuconazonium Sulfate →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Isavuconazonium sulfate is used for the treatment of invasive fungal infections, particularly invasive aspergillosis and invasive mucormycosis, in adult patients who require systemic antifungal therapy.
Isavuconazonium sulfate is a water-soluble prodrug that is rapidly converted in the body to isavuconazole, a broad-spectrum triazole antifungal agent that inhibits fungal cell membrane synthesis.
Isavuconazonium sulfate is marketed under the trade name Cresemba.
Isavuconazonium sulfate (Cresemba) is manufactured by Astellas Pharma, depending on regional regulatory approvals.
The generic name of the product is isavuconazonium sulfate.
A commonly recognized brand name of isavuconazonium sulfate is Cresemba.
Isavuconazonium sulfate is manufactured in various countries including the USA, EU member states, and other regions, depending on the approved manufacturing site and market authorization.
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