Naftifine Hydrochloride Suppliers & Bulk Manufacturers
Available Forms: Cream / Gel
Available Strengths: 1 %, 2%
Reference Brands: Naftin (USA), Xolafin (USA)
Category:
Anti-fungal
Naftifine Hydrochloride is available in Cream / Gel
and strengths such as 1 %, 2%.
Sourced from GMP-certified and ISO-compliant manufacturers, this API meets
global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical
formulation and commercial manufacturing, Naftifine Hydrochloride is supplied in
bulk quantities with complete regulatory support including DMF, COA, and MSDS.
|
Technical Specifications & Supply Details
|
| Lead Time |
7 to 60 days (depending on batch size & schedule) |
| MOQ |
As per manufacturer’s batch size |
| COA |
Available with every batch |
| Regulatory Dossier / DMF |
Available upon request |
| Export Documentation |
FSC, COA, Manufacturing License, Product Permission |
| Standards |
IP, BP, USP |
| Certifications |
WHO-GMP, EU-GMP, USFDA (as applicable) |
Naftifine Hydrochloride can be exported to over 30 countries across Asia, Africa, Europe,
and Latin America. Flexible packaging, competitive pricing, and a verified supplier
network make Pharmatradz a trusted sourcing partner for pharmaceutical companies
and contract manufacturers worldwide.
Product Description:
Naftifine is a topical antifungal agent known for its triple action, providing antifungal, antibacterial, and anti-inflammatory effects. Its antifungal activity is primarily based on the inhibition of the squalene-2,3-epoxidase enzyme, a key enzyme involved in the biosynthesis of ergosterol. Ergosterol is an essential component of fungal cell membranes, and inhibition of its production leads to disruption of normal fungal cell membrane formation.
In certain fungal species, naftifine also exhibits fungicidal activity due to the accumulation of squalenes within the fungal cells. This buildup causes structural damage to the fungal cell membranes, including the endoplasmic reticulum, ultimately leading to fungal cell death. Naftifine demonstrates predominantly fungicidal activity against dermatophytes and molds, while showing mainly fungistatic activity against yeasts.
In addition to its antifungal properties, naftifine has proven antibacterial activity, making it effective in the treatment of bacterial skin infections such as pyoderma. Its combined antifungal, antibacterial, and anti-inflammatory actions make naftifine a valuable option for managing mixed or complicated skin infections.
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