Naftifine Hydrochloride 1 %, 2% Suppliers & Bulk Manufacturers
Available Forms: Cream / Gel
Available Strengths: 1 %, 2%
Reference Brands: Naftin (USA), Xolafin (USA)
Category: Anti-fungal
Naftifine Hydrochloride is a Anti-fungal product available as Cream / Gel in strengths 1 %, 2%. It corresponds to the reference brands Naftin (USA), Xolafin (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Naftifine is a topical antifungal agent known for its triple action, providing antifungal, antibacterial, and anti-inflammatory effects. Its antifungal activity is primarily based on the inhibition of the squalene-2,3-epoxidase enzyme, a key enzyme involved in the biosynthesis of ergosterol. Ergosterol is an essential component of fungal cell membranes, and inhibition of its production leads to disruption of normal fungal cell membrane formation.
In certain fungal species, naftifine also exhibits fungicidal activity due to the accumulation of squalenes within the fungal cells. This buildup causes structural damage to the fungal cell membranes, including the endoplasmic reticulum, ultimately leading to fungal cell death. Naftifine demonstrates predominantly fungicidal activity against dermatophytes and molds, while showing mainly fungistatic activity against yeasts.
In addition to its antifungal properties, naftifine has proven antibacterial activity, making it effective in the treatment of bacterial skin infections such as pyoderma. Its combined antifungal, antibacterial, and anti-inflammatory actions make naftifine a valuable option for managing mixed or complicated skin infections.
Naftifine Hydrochloride — third party manufacturing & bulk supply
Naftifine Hydrochloride 1 %, 2% is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Naftifine Hydrochloride listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Naftifine Hydrochloride →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Naftifine is used to treat fungal skin infections such as athlete’s foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis).
Naftifine is a synthetically manufactured antifungal agent produced through chemical synthesis.
Naftifine is sold under trade names such as Naftin and Xolafin, depending on the market.
Naftin was originally marketed by Merz Pharmaceuticals. Generic versions are manufactured by multiple pharmaceutical companies worldwide.
The generic name of Naftifine is naftifine hydrochloride.
Brand names of Naftifine include Naftin and Xolafin, along with generic equivalents.
Naftifine is manufactured in several countries including the United States, India, and European nations, depending on the manufacturer and regulatory approvals.
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