Flucytosine 250 mg, 50 mg/ml Suppliers & Bulk Manufacturers

Available Forms: Capsules / Oral Solution

Available Strengths: 250 mg, 50 mg/ml

Reference Brands: Ancobon (USA)

Category: Anti-fungal

Flucytosine (5-FC) is an antifungal used with amphotericin B for cryptococcal meningitis and some serious Candida infections. WHO lists it as an essential medicine, and access in Africa and Asia has long been limited. It is supplied as 250 and 500 mg capsules and as an infusion; the original brand is Ancobon. Ask PharmaTradz for a quote; we confirm the manufacturer, registration documents and lead time for your country.

Product Description:

Flucytosine, also known as 5-fluorocytosine (5-FC) and marketed under the brand name Ancobon, is an antifungal medication used for the treatment of serious systemic fungal infections, including Candida infections and cryptococcosis. As an antimetabolite, flucytosine specifically targets fungal cells by interfering with DNA and RNA synthesis, while sparing mammalian cells, which enhances its safety profile.

Flucytosine is commonly administered in combination with another antifungal agent, such as amphotericin B, to prevent the development of fungal resistance. Its use as a monotherapy is generally discouraged due to the risk of resistance. The medication can be administered orally or intravenously, depending on the severity and type of infection.

Clinical monitoring is essential during treatment, particularly because flucytosine is primarily excreted by the kidneys. Dose adjustments are required in patients with impaired renal function to minimize the risk of toxicity. With careful medical supervision, flucytosine provides an effective option for managing severe and systemic fungal infections, offering both efficacy and a favorable safety profile.