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Hydroxypropyl Methylcellulose bulk supplier for pharma manufacturers

Hydroxypropyl Methylcellulose K15M, K100M Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: K15M, K100M

Reference Brands: METHOCEL (USA), Benecel (EU/UK)

Category: Pharmaceutical Excipients

Hydroxypropyl Methylcellulose is a Pharmaceutical Excipients product available as Powder in strengths K15M, K100M. It corresponds to the reference brands METHOCEL (USA), Benecel (EU/UK). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Hydroxypropyl methylcellulose, commonly known as hypromellose (HPMC), is a semisynthetic, inert, and viscoelastic polymer widely used in the pharmaceutical, ophthalmic, and food industries. It is derived from cellulose and modified to improve its solubility, stability, and functional performance in various formulations. In pharmaceuticals, hypromellose serves primarily as an excipient and controlled-release agent in oral solid dosage forms such as tablets and capsules, helping regulate the release of active ingredients over time and improving product stability.

In ophthalmic preparations, hypromellose is frequently used in lubricating eye drops and artificial tears to relieve dryness and irritation by forming a protective film over the surface of the eye. Its excellent film-forming and thickening properties make it useful in improving the viscosity and retention time of eye care products. Additionally, hypromellose is widely utilized in nutraceutical and pharmaceutical coatings, including vegetarian capsule shells as an alternative to gelatin.

Beyond pharmaceuticals, hypromellose is also approved as a food additive (E464) where it functions as an emulsifier, stabilizer, thickening agent, and suspending agent. Due to its safety profile, compatibility with many ingredients, and versatile functionality, hypromellose remains an important multifunctional excipient used in a wide range of healthcare and industrial applications.

Hydroxypropyl Methylcellulose — third party manufacturing & bulk supply

Hydroxypropyl Methylcellulose K15M, K100M is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Hydroxypropyl Methylcellulose listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Hydroxypropyl Methylcellulose (Hypromellose) is used as a pharmaceutical excipient in tablets, capsules, controlled-release drug delivery systems, coating agents, ophthalmic lubricants, and as a thickening and stabilizing agent in oral and topical formulations.

Hydroxypropyl Methylcellulose is derived from purified cellulose obtained from plant fibers such as wood pulp or cotton, which is chemically modified with methyl and hydroxypropyl groups to improve solubility and functionality.

Common trade names include METHOCEL, Benecel, and Pharmacoat, depending on the manufacturer and grade.

Major manufacturers include Dow (IFF), Ashland, Shin-Etsu Chemical, and several global excipient manufacturers supplying pharmaceutical grade HPMC.

The generic (compendial) name is Hypromellose (Hydroxypropyl Methylcellulose).

Common excipient brand names include METHOCEL, Benecel, and Pharmacoat.

Hydroxypropyl Methylcellulose is manufactured globally in countries such as the United States, Japan, Germany, China, and India by pharmaceutical excipient manufacturers supplying regulated markets worldwide.

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