Croscarmellose Sodium bulk supplier for pharma manufacturers

Croscarmellose Sodium 2–5% Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: 2–5%

Reference Brands: Generic formulations

Croscarmellose Sodium is a Pharmaceutical Excipients product available as Powder in strengths 2–5%. It corresponds to the reference brand Generic formulations. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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Product Description:

Croscarmellose sodium is a cross-linked cellulose derivative widely used as a pharmaceutical excipient, particularly as a superdisintegrant in tablet and capsule formulations. The cross-linking process reduces its water solubility while allowing the material to rapidly absorb water and swell significantly, similar to a sponge. This unique property enables tablets to break apart quickly after administration, improving the dissolution of active pharmaceutical ingredients and helping them come into better contact with bodily fluids for effective absorption.

In pharmaceutical manufacturing, croscarmellose sodium is valued for its ability to enhance drug release and overall bioavailability. It is commonly used in immediate-release tablets, nutraceutical products, and dietary supplements to ensure that the dosage form disintegrates efficiently in the gastrointestinal tract. Without an effective disintegrating agent, tablets may dissolve too slowly or in an unintended part of the digestive system, which can reduce the effectiveness of the medication.

Another important advantage of croscarmellose sodium is its functional stability during formulation and storage. It performs reliably even in tablets with higher hardness and maintains consistent disintegration performance over time. Due to its safety profile and effectiveness, croscarmellose sodium is widely approved for pharmaceutical use and remains one of the most commonly used excipients in modern tablet manufacturing.

Croscarmellose Sodium — third party manufacturing & bulk supply

Croscarmellose Sodium 2–5% is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Croscarmellose Sodium is supplied as Powder — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Croscarmellose Sodium listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Croscarmellose sodium is used as a superdisintegrant in tablet and capsule formulations to help tablets break apart quickly after ingestion, improving drug dissolution and absorption.

Croscarmellose sodium is made from sodium carboxymethylcellulose that has been chemically cross-linked to enhance its swelling and disintegration properties.

Common trade names include Ac-Di-Sol, Primellose, and Nymcel ZSX, depending on the manufacturer and grade.

Croscarmellose sodium is manufactured by several pharmaceutical excipient producers worldwide, including DuPont, DFE Pharma, IFF, and other global excipient manufacturers.

The generic name is Croscarmellose Sodium (cross-linked sodium carboxymethylcellulose).

Well-known brand names include Ac-Di-Sol, Primellose, and Nymcel ZSX.

Croscarmellose sodium is manufactured globally in pharmaceutical excipient production facilities located in the United States, Germany, India, China, and other regions with pharmaceutical manufacturing industries.