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Crospovidone bulk supplier for pharma manufacturers

Crospovidone Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: Type A, Type B, XL, XL-10, CL, CL-F

Reference Brands: Generic formulations marketed under different names

Category: Pharmaceutical Excipients

Crospovidone is a Pharmaceutical Excipients product available as Powder in strengths Type A, Type B, XL, XL-10, CL, CL-F. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Crospovidone and microcrystalline cellulose (MCC) are widely used pharmaceutical excipients that function primarily as fillers and formulation aids in many oral solid dosage forms. These substances are considered pharmacologically inactive and are incorporated into medicines to improve drug delivery, stability, and manufacturing efficiency. Crospovidone, a cross-linked polymer of polyvinylpyrrolidone, is mainly used as a superdisintegrant that helps tablets break apart rapidly after ingestion, thereby enhancing the dissolution and absorption of the active drug. Microcrystalline cellulose, derived from purified cellulose, is commonly used as a filler, binder, and stabilizer that improves tablet hardness and uniformity.

Both crospovidone and MCC are widely used in pharmaceutical tablets, capsules, and nutraceutical products due to their excellent compatibility with active pharmaceutical ingredients and their safety profile. These excipients help maintain consistent dosage, improve the mechanical strength of tablets, and support efficient large-scale manufacturing processes. In pharmaceutical and clinical research, these materials are also recognized for their distinct physical and microscopic characteristics, which allow them to be identified when present in biological samples. Overall, crospovidone and microcrystalline cellulose remain important excipients in modern drug formulation, supporting effective drug delivery while maintaining product quality and stability.

Crospovidone — third party manufacturing & bulk supply

Crospovidone is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Crospovidone listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Crospovidone is used as a superdisintegrant in tablet and capsule formulations. It helps tablets break apart quickly after administration, which improves drug dissolution and absorption.

Crospovidone is made from cross-linked polyvinylpyrrolidone, a polymer derived from the monomer N-vinylpyrrolidone that has been chemically cross-linked to make it insoluble but highly absorbent.

Common trade names include Polyplasdone, Kollidon CL, Kollidon CL-M, and Vivapharm Crospovidone.

Crospovidone is manufactured by several excipient companies worldwide, including Ashland, BASF, JRS Pharma, and other pharmaceutical excipient manufacturers.

The generic name is Crospovidone (cross-linked polyvinylpyrrolidone).

Well-known brand names include Polyplasdone and Kollidon CL series depending on the manufacturer and grade.

Crospovidone is manufactured globally in pharmaceutical excipient production facilities located in the United States, Germany, India, China, and several European countries.

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