Microcrystalline Cellulose PH 101 / PH 102 grades Suppliers & Bulk Manufacturers

Available Forms: Powder / Granules

Available Strengths: PH 101 / PH 102 grades

Reference Brands: -

Category: Pharmaceutical Excipients

Microcrystalline cellulose (MCC) is one of the most widely used tablet fillers and binders, made from purified wood pulp. It is sold in grades that differ in particle size and moisture, such as PH 101, PH 102, PH 112 and PH 200. We source pharmacopoeial grade MCC (USP-NF, Ph. Eur., IP) from manufacturers in India, with batch Certificates of Analysis and supplier documents.

Product Description:

Microcrystalline cellulose (MCC) is a purified, partially depolymerized form of cellulose derived from refined wood pulp. It is widely used across the pharmaceutical, food, and nutraceutical industries due to its excellent functional and stability properties. MCC appears as a fine, white, odorless powder and is valued for its ability to act as a reliable excipient in various formulations. In pharmaceutical manufacturing, it is commonly used in tablets and capsules as a binder, filler, and disintegrant, helping to improve compressibility and ensure uniform distribution of active ingredients.

In the food industry, microcrystalline cellulose serves multiple roles such as a texturizer, anti-caking agent, fat substitute, emulsifier, extender, and bulking agent. These properties make it useful in processed foods where improved texture, stability, and consistency are required. It helps maintain product quality while supporting formulation efficiency in large-scale production.

MCC is also widely used in vitamin supplements and nutraceutical tablets because of its compatibility with a wide range of active ingredients and its ability to enhance tablet strength and stability. Additionally, in research and laboratory applications, microcrystalline cellulose can be used in plaque assays for counting viruses as an alternative to carboxymethylcellulose. Due to its versatility, safety profile, and functional benefits, microcrystalline cellulose remains an important material in modern pharmaceutical and food manufacturing.

MCC grades and what they are for

• PH 101: fine powder, used in wet granulation and for making spheres (pellets).
• PH 102: coarser powder that flows better, widely used in direct compression.
• PH 112: low-moisture grade for moisture-sensitive drugs.
• PH 200: large particles for better flow in direct compression.

The grade names come from the original Avicel range, and other makers sell equivalent grades. Silicified MCC, co-processed with colloidal silicon dioxide, is also available for better flow.

MCC manufacturing in India

India has several MCC manufacturers supplying domestic and export markets. When you buy, ask for the monograph (USP-NF, Ph. Eur. or IP), particle size, bulk density and loss on drying for the grade, microbial limits, the supplier's excipient GMP certification, and an undertaking to notify you of process changes.

Our explainer on what an excipient is and why quality matters covers excipient sourcing, and our tablet contract manufacturing page covers finished-product supply. Send us an RFQ with the grade, quantity and pack size.