Available Forms: Oral suspension
Available Strengths: 8.86 mg/mL
Reference Brands: Duvyzat (USA/EU)
Category: Neurology
Givinostat is a histone deacetylase (HDAC) inhibitor which works by inhibiting class I and II HDAC enzymes, reducing inflammation, muscle degeneration and fibrosis in patients with Duchenne muscular dystrophy. It is indicated for patients aged 6 years and older with DMD, regardless of specific genetic variant. The medication is given as a twice daily oral suspension with food, and requires monitoring of blood counts and triglycerides due to risks of thrombocytopenia and hypertriglyceridaemia.
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Strength: 125 mg/mL, 200 mg, 250 mg, 300 mg, 500 mg, 100 mg/mL
Form: Tablet / Capsule/ Injection / Oral syrup
Reference Brands: Depakene (USA), Depakine (EU/LATAM), Valprol (India)
Strength: 50 mg, 100 mg
Form: Tablets
Reference Brands: Ubrelvy (USA/India)
Strength: 100 mg
Reference Brands: Tasmar (USA/EU)
Strength: 50 mg ,100 mg
Reference Brands: Xadago (USA/EU)
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