Drotaverine / Mefenamic Acid Tablet bulk supplier for pharma manufacturers

Drotaverine / Mefenamic Acid Tablet 80mg + 250mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 80mg + 250mg

Reference Brands: -

Category: Analgesic

Drotaverine 80 mg and mefenamic acid 250 mg tablets, an antispasmodic and NSAID combination for menstrual cramps and colicky pain. For licensed importers, distributors and hospital pharmacies in markets that register it.

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Product Description:

This tablet pairs drotaverine hydrochloride 80 mg, an antispasmodic related to papaverine, with mefenamic acid 250 mg, a fenamate NSAID. Drotaverine inhibits phosphodiesterase 4 in smooth muscle, which raises cyclic AMP and relaxes the gut, biliary tract, ureter and uterus without anticholinergic effects such as dry mouth. Mefenamic acid blocks prostaglandin synthesis, the main driver of menstrual pain. Drotaverine is not authorised in the United States, and this pairing is registered in a limited number of markets.

Prescribers use it for spasmodic pain: primary dysmenorrhoea above all, and also intestinal, biliary and renal colic. It is taken with or after food, usually up to three times a day for a few days. Mefenamic acid brings the usual NSAID cautions: peptic ulcer, gastrointestinal bleeding, NSAID-triggered asthma, renal and hepatic impairment, heart failure and late pregnancy, and treatment stops if diarrhoea or rash develops. Drotaverine is avoided in severe heart failure and second- or third-degree heart block, and it can lower blood pressure.

Sourcing notes. Because few markets register this pair, start by checking that your regulator accepts it; the dossier will usually need a rationale for the fixed combination. Expect CTD or ACTD format with zone IVb stability data for hot humid markets. Tablets come in alu-alu or PVC/alu blister strips, stored at room temperature with no cold chain. Ask for a CoA per batch with assay, dissolution and related substances for both actives, plus the GMP certificate and a CoPP. It is prescription-only. Your enquiry should state strength, pack size, coating and label language.

Drotaverine / Mefenamic Acid Tablet — third party manufacturing & bulk supply

Drotaverine / Mefenamic Acid Tablet 80mg + 250mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Drotaverine / Mefenamic Acid Tablet is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Drotaverine / Mefenamic Acid Tablet listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.

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Frequently Asked Questions

Drotaverine + Mefenamic Acid is used to relieve abdominal pain, menstrual cramps, gastrointestinal spasms, and other spasm-related pain conditions. It helps reduce smooth-muscle spasms, lowers inflammation, and provides effective relief from acute pain episodes.

It contains two active ingredients: drotaverine, an antispasmodic agent that relaxes smooth muscles, and mefenamic acid, a non-steroidal anti-inflammatory drug that helps relieve pain and inflammation.

It is marketed under various trade names such as Dovenrin-M, Drotikind-M, and other region-specific brands. Brand names differ by manufacturer and market.

Several pharmaceutical companies manufacture this combination. The manufacturer varies by region. It is also made by other manufacturers, including in India. We match each enquiry with licensed makers whose documents fit your market.

The generic name of the product is drotaverine and mefenamic acid.

It is sold under multiple brand names such as Dovenrin-M and Drotikind-M, along with other similar brands depending on the manufacturer and market.

It is manufactured in several countries, with India being one of the major production hubs due to its strong pharmaceutical industry. The exact location depends on the manufacturing company.