Cholecalciferol Suppliers & Bulk Manufacturers

Available Forms: Powder

Available Strengths: -

Reference Brands:

Category: Nutraceuticals

Cholecalciferol (vitamin D3) powder is the raw material for vitamin D tablets, capsules, sachets, drops and fortified foods. It is supplied in pharmaceutical and food grades, including stabilised beadlets and powders of 100,000 IU/g and 500,000 IU/g. PharmaTradz sources it for formulators and supplement makers with CoA and pharmacopoeia compliance.

Product Description:

Cholecalciferol, vitamin D3, is the form of vitamin D made in the skin in response to sunlight. It is converted in the liver to calcifediol, then in the kidney to calcitriol, the active hormone that regulates calcium and phosphate absorption and bone mineralisation. It is used to prevent and treat vitamin D deficiency, which is common in people with little sun exposure, darker skin, older age or obesity.

Supplementation corrects deficiency and prevents rickets and osteomalacia. Large trials in people who were not deficient have not shown broad benefits for fractures, cancer or cardiovascular disease, so supplementation is best targeted at people with low levels or high risk. Toxicity is uncommon but real: prolonged high doses cause hypercalcaemia, with nausea, confusion and kidney damage.

Sourcing notes. Cholecalciferol powder is supplied in several forms for manufacturers. Pure crystalline cholecalciferol is extremely potent and toxic in small amounts, so it is handled as a stabilised dry powder or beadlet diluted to a set strength, such as 100,000 IU per gram, with an antioxidant and carrier. The buyer must specify strength, carrier (for example gelatin or acacia, which matters for vegetarian and halal claims) and the pharmacopoeial grade required. Pharmaceutical and feed grades are not interchangeable.