Chloramphenicol Sodium Succinate Injection 1 gm Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 1 gm

Reference Brands: Generic formulations marketed under different names

Category: Antibiotics

Chloramphenicol Sodium Succinate is a prescription medicine used to treat the symptoms of serious bacterial infection. Chloramphenicol Sodium Succinate may be used alone or with other medications. Chloramphenicol Sodium Succinate belongs to a class of drugs called Antibiotics, Other.

Product Description:

Chloramphenicol is a broad-spectrum bacteriostatic antibiotic inhibiting bacterial protein synthesis at the 50S ribosomal subunit. The sodium succinate ester is the water-soluble prodrug used for injection, hydrolysed in vivo to active chloramphenicol.

Its safety profile determines everything about how it is used. Chloramphenicol causes two distinct haematological toxicities: a dose-related, reversible bone marrow suppression, and an idiosyncratic, dose-independent aplastic anaemia that is frequently fatal and may appear weeks after treatment ends. In neonates, immature glucuronidation causes accumulation and the circulatory collapse known as grey baby syndrome. These effects removed it from routine use in high-income countries decades ago.

It nevertheless remains important where alternatives are unavailable or unaffordable: bacterial meningitis, typhoid and rickettsial infection in resource-limited settings, and it appears on the WHO Model List of Essential Medicines for exactly that reason.

Sourcing notes. Demand is concentrated in public health and donor-funded procurement rather than commercial channels. Labelling must carry the haematological warnings in full and in the destination language; this is not a place for abbreviation. Manufacture requires sterile powder-filling approval at the specific plant. WHO classifies chloramphenicol under Access.