Ceftazidime + Sulbactam Injection 1500mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 1500mg

Reference Brands: Generic formulations marketed under different names

Category: Antibiotics

Ceftazidime+Sulbactam is used in the treatment of bacterial infections. Ceftazidime + Sulbactam is a combination of two medicines: Ceftazidime and Sulbactam. Ceftazidime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria.

Product Description:

This fixed-dose combination pairs ceftazidime, a third-generation anti-pseudomonal parenteral cephalosporin, with sulbactam, a beta-lactamase inhibitor. The rationale offered is restoration of ceftazidime activity against beta-lactamase-producing organisms.

The construction requires verification before it is quoted. Sulbactam's inhibitory spectrum does not cover the enzymes that most often defeat ceftazidime — the extended-spectrum and AmpC beta-lactamases — and the internationally approved ceftazidime combination pairs it with avibactam, a diazabicyclooctane inhibitor with a quite different and much broader inhibitory profile. Ceftazidime-avibactam is approved in the United States, European Union and elsewhere on the basis of substantial trial evidence. Ceftazidime-sulbactam is marketed in India and some neighbouring markets and is not approved in any stringent regulatory jurisdiction.

Sourcing notes. Establish whether the buyer means ceftazidime-sulbactam or ceftazidime-avibactam; the names are similar, the products are not, and the substitution is not a matter of preference. Verify current Indian licence status for the exact ratio quoted, since antibiotic fixed-dose combinations have been a focus of regulatory action. For any regulated market, the avibactam combination is the registrable product. Manufacture requires sterile powder-filling approval at the specific plant.