Capsofungin Acetate For Injection 50mg/vial, 70ml/vial Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 50mg/vial, 70ml/vial

Reference Brands: Cancidas (USA/EU)

Category: Antibiotics

Caspofungin injection is used to treat serious fungal infections, including candidemia (fungal infection in the blood), esophageal candidiasis (fungal infection of the esophagus), other candida infections, and aspergillosis (fungal infection in the lungs).

Product Description:

Caspofungin is an echinocandin antifungal, and its inclusion in an antibiotics listing reflects catalogue convention rather than pharmacology. It inhibits synthesis of beta-1,3-glucan, an essential component of the fungal cell wall with no mammalian counterpart, which gives the class a favourable safety profile relative to amphotericin B and the azoles.

It is first-line therapy for invasive candidiasis and candidaemia, and is used empirically in febrile neutropenia and as salvage therapy in invasive aspergillosis. Echinocandins are the preferred class where Candida glabrata or Candida krusei is suspected, since both show reduced azole susceptibility.

It is supplied as lyophilised powder for injection at 50 and 70 mg, given as a loading dose followed by daily maintenance, and requires reconstitution and dilution before infusion.

Sourcing notes. Caspofungin came off patent and generics are now available from several manufacturers, so this is a genuinely sourceable product rather than an innovator-only one. Manufacture requires lyophilisation capability, which is a materially narrower approval than sterile liquid filling and is held by fewer sites. Confirm the specific plant is approved for lyophilised products. The reconstituted product has limited stability, which matters for tender specifications covering hospital handling.