Brentuximab Vedotin 50 mg/vial Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 50 mg/vial
Reference Brands: Adcetris (USA/EU)
Category: Oncology Cancer Care
Brentuximab Vedotin is a monoclonal antibody–drug conjugate (ADC) that targets CD30-expressing cancer cells. It delivers a cytotoxic agent directly to malignant cells, helping to kill them while minimizing damage to normal tissue.
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Product Description:
Brentuximab vedotin is an antibody-drug conjugate: an anti-CD30 antibody linked to monomethyl auristatin E, a microtubule-disrupting agent far too toxic to give on its own. The antibody delivers it to CD30-expressing cells, where the conjugate is internalised and a protease-cleavable linker releases the payload inside the cell. The design turns an unusable poison into a targeted therapy.
It is used for Hodgkin lymphoma, systemic anaplastic large cell lymphoma and other CD30-expressing T-cell lymphomas, in first-line combinations and after relapse. Its arrival changed outcomes in relapsed Hodgkin lymphoma substantially. Peripheral sensory neuropathy is the characteristic dose-limiting toxicity, cumulative and often requiring dose reduction. Progressive multifocal leukoencephalopathy carries a boxed warning, and the combination with bleomycin is contraindicated because of pulmonary toxicity. Neutropenia, infusion reactions and tumour lysis occur.
Sourcing notes. Originator biologic, on patent, no biosimilar. Cold chain, supplied as lyophilised powder for reconstitution. As an antibody-drug conjugate it is handled as a cytotoxic in pharmacy despite being an antibody — a point buyers sometimes miss. CD30 expression testing guides use.
Brentuximab Vedotin — third party manufacturing & bulk supply
Brentuximab Vedotin 50 mg/vial is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Brentuximab Vedotin is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Brentuximab Vedotin listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
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