Bexarotene 75 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 75 mg

Reference Brands: Targretin (USA/EU)

Category: Oncology Cancer Care

Bexarotene is a retinoid X receptor (RXR) agonist used in the treatment of cutaneous T-cell lymphoma (CTCL), a type of skin cancer. It works by regulating the expression of genes that control cell growth, differentiation, and apoptosis (cell death), thereby slowing or stopping the growth of cancer cells.

Product Description:

Bexarotene is an antineoplastic (anti-cancer) medicine sold under the brand name Targretin and is primarily used in the treatment of cutaneous T-cell lymphoma (CTCL), a rare type of non-Hodgkin lymphoma that mainly affects the skin. It belongs to the third generation of retinoids and works by selectively activating retinoid X receptors, which regulate gene expression involved in cell growth, differentiation, and programmed cell death. Through this targeted action, bexarotene helps slow the proliferation of malignant T-cells and reduces skin lesion severity.

Bexarotene is available in both systemic and topical forms. The oral form is indicated for patients with CTCL whose disease has not responded to at least one prior systemic therapy. The topical form is used for the treatment of skin lesions in patients with refractory or persistent CTCL, or in those who cannot tolerate other available treatments. Therapy with bexarotene requires medical supervision and regular monitoring, as it can affect lipid levels, thyroid function, and liver parameters. It is an important option in advanced or treatment-resistant CTCL management.