Alverine Citrate 60 mg, 120 mg Suppliers & Bulk Manufacturers

Available Forms: capsules

Available Strengths: 60 mg, 120 mg

Reference Brands: Spasmonal (USA), Meteospasmyl (EU)

Category: Gastrointestinal Drugs

Alverine Citrate is a smooth muscle relaxant used to relieve abdominal pain, cramps, and spasms associated with irritable bowel syndrome (IBS) and other gastrointestinal disorders. It works by relaxing the smooth muscles of the gut, helping to reduce discomfort and improve digestive comfort.

Product Description:

Alverine citrate is a direct-acting smooth muscle relaxant. It reduces the sensitivity of gut and uterine smooth muscle to contractile stimuli, and it also acts as a 5-HT1A antagonist, which appears to reduce visceral sensitivity — the heightened perception of normal gut activity that underlies much of the pain in irritable bowel syndrome. It does not have the anticholinergic effects of drugs such as hyoscine or dicycloverine, so dry mouth, blurred vision and urinary retention are not problems.

It is used for abdominal pain and spasm in irritable bowel syndrome and other functional bowel disorders, and for primary dysmenorrhoea. Adverse effects are generally mild — nausea, dizziness, headache and itching — but rare hepatitis and jaundice have been reported, and treatment should stop if they occur. It is contraindicated in paralytic ileus and intestinal obstruction. It is also sold in combination with simeticone in some European markets.

Sourcing notes. Registered in the UK and several European, Middle Eastern and Asian markets, often over the counter, but not in the United States. Buyers should confirm whether they need single-ingredient alverine or the simeticone combination, since they are separate registrations. Hard-gelatin capsules are standard, and the manufacturing and supplier base is reasonable, so price competition is real.