Alclometasone Dipropionate 0.05% Suppliers & Bulk Manufacturers

Available Forms: Ointment

Available Strengths: 0.05%

Reference Brands: Aclovate (USA/EU)

Category: Derma Drugs

Alclometasone is a low-potency topical corticosteroid used to treat inflammatory and allergic skin conditions such as eczema, dermatitis, and psoriasis. It works by reducing inflammation, redness, swelling, and itching caused by skin reactions. Available as a 0.05% cream or ointment, it is applied directly to the affected area once or twice daily. Because of its mild potency, it is suitable for sensitive skin areas, including the face and intertriginous regions.

Product Description:

Alclometasone dipropionate is a low-potency topical corticosteroid. Like all topical steroids it binds intracellular glucocorticoid receptors and switches off the transcription of inflammatory genes, reducing redness, swelling and itch. Its structure was designed to give useful anti-inflammatory activity with limited skin atrophy, which is why it sits in the mildest effective tier above hydrocortisone.

It is used for mild to moderate eczema, dermatitis and psoriasis, and its potency makes it suitable where stronger steroids are risky: the face, eyelids, flexures, genital skin and in young children, all sites where the skin is thin and absorption is high. It is applied thinly twice daily for a limited period. Even at low potency, prolonged use on thin skin causes atrophy, telangiectasia, striae and perioral dermatitis, and occlusion or large surface areas increase systemic absorption. It should not be used on untreated bacterial, fungal or viral skin infection.

Sourcing notes. Off patent. Cream and ointment are separate registrations and are not interchangeable in practice — ointment is more occlusive and more potent in effect, cream more acceptable on weeping or hairy skin. Tube sizes differ by market, and pack size often determines whether a tender is competitive.