Trimethobenzamide Hydrochloride 200 mg , 200 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Capsules / Injection

Available Strengths: 200 mg , 200 mg/mL

Reference Brands: Tigan (USA)

Category: Antiemetic

Trimethobenzamide Hydrochloride is a Antiemetic product available as Capsules / Injection in strengths 200 mg , 200 mg/mL. It corresponds to the reference brand Tigan (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Trimethobenzamide is an antiemetic medication that works primarily as an antagonist of dopamine D2 receptors. Its therapeutic action is believed to occur at the chemoreceptor trigger zone (CTZ) located in the medulla oblongata of the brain. By blocking dopamine-mediated signals in this area, trimethobenzamide helps suppress the neural pathways responsible for triggering nausea and vomiting.

Through its targeted action on the central nervous system, trimethobenzamide is effective in controlling nausea and vomiting associated with various medical conditions, including postoperative recovery, gastrointestinal disturbances, and medication-induced emesis. Unlike some other antiemetic agents, trimethobenzamide has minimal effect on gastric motility, making it suitable for patients who require symptom relief without significant gastrointestinal stimulation.

Trimethobenzamide is commonly administered in oral or injectable form, depending on the severity of symptoms and clinical setting. The drug is generally well tolerated when used under medical supervision, although monitoring is recommended to manage potential central nervous system or anticholinergic side effects. Its established mechanism of action makes trimethobenzamide a reliable option in antiemetic therapy.