Dimenhydrinate Tablets 50 mg, 100 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 50 mg, 100 mg

Reference Brands: Dramamine(US & EU)

Category: Antiemetic

Dimenhydrinate 50 mg and 100 mg tablets, an antihistamine for motion sickness, nausea and vertigo. For pharmacy wholesalers, importers and distributors registering or restocking a pharmacy or over-the-counter antiemetic.

Product Description:

Dimenhydrinate is a salt of diphenhydramine, a first-generation H1 antihistamine, with 8-chlorotheophylline, a mild stimulant added to counter some of the drowsiness. Diphenhydramine blocks histamine and acetylcholine signalling in the balance organs and the brain's vomiting centre, which is why it settles nausea triggered by movement. This page covers plain oral tablets at 50 mg and 100 mg. Tablets suit travellers who can plan a dose ahead of a journey; injections and suppositories serve patients who are already vomiting.

The main use is relief and prevention of the nausea, vomiting and dizziness of motion sickness. The first dose is taken 30 to 60 minutes before travel. Adults usually take 50 to 100 mg every four to six hours, up to 400 mg in 24 hours. Drowsiness is common, so patients should not drive, and alcohol adds to it. Its anticholinergic action needs care in narrow-angle glaucoma, urinary retention and confused elderly patients. It can also mask early signs of ear damage from aminoglycosides.

Sourcing notes. Dimenhydrinate tablets are sold without prescription in many markets and are pharmacy-only in others, so check the legal category and labelling rules first. Specify strength, scored or plain tablets, blister or bottle, and pack size. Request the CTD or ACTD dossier, stability data for your climatic zone (Zone IVb for hot, humid markets) and a certificate of analysis for each batch with assay, dissolution and related substances. A GMP certificate and CoPP support registration. For over-the-counter sale, ask for artwork in your language.