Tafenoquine Succinate 150 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 150 mg

Reference Brands: Krintafel (USA)

Category: Antiemetic

Tafenoquine Succinate is a Antiemetic product available as Tablets in strengths 150 mg. It corresponds to the reference brand Krintafel (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Tafenoquine is a long-acting antimalarial medication used for both the prevention and treatment of malaria. It is especially important in the management of Plasmodium vivax malaria, where it is administered alongside a blood-stage antimalarial drug such as chloroquine to prevent disease relapse. Tafenoquine is also approved for malaria prophylaxis and can be used to help prevent all types of malaria in adults traveling to endemic regions.

The primary therapeutic advantage of tafenoquine lies in its ability to eliminate the dormant liver-stage parasites known as hypnozoites, which are responsible for recurrent infections caused by Plasmodium vivax and Plasmodium ovale. These hypnozoites can persist in the liver even after successful clearance of parasites from the bloodstream, leading to repeated episodes of malaria if not treated effectively. Tafenoquine belongs to the 8-aminoquinoline class of antimalarial agents and offers a significant benefit over primaquine, as it has a prolonged half-life of approximately two to three weeks, allowing for a single-dose treatment regimen rather than a 14-day course.

Due to the risk of hemolytic anemia, tafenoquine must only be used after confirming normal glucose-6-phosphate dehydrogenase (G6PD) activity. When prescribed appropriately, tafenoquine provides a convenient and effective option for the radical cure and prevention of relapsing malaria.