Meclizine Hydrochloride 12.5 mg, 25 mg, 50 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 12.5 mg, 25 mg, 50 mg
Reference Brands: Antivert (USA), Bonine (USA)
Category: Antiemetic
Meclizine Hydrochloride is a Antiemetic product available as Tablets in strengths 12.5 mg, 25 mg, 50 mg. It corresponds to the reference brands Antivert (USA), Bonine (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Meclizine Hydrochloride is the hydrochloride salt form of meclizine, a synthetic piperazine derivative with antiemetic, sedative, and histamine H1 receptor–blocking properties. It functions primarily as an antihistamine by inhibiting the action of histamine at H1 receptors, thereby preventing symptoms associated with histamine release such as vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. Through these actions, meclizine helps reduce nausea, vomiting, and dizziness related to vestibular disturbances.
In addition to its antihistaminic activity, Meclizine Hydrochloride exhibits anticholinergic effects and may act directly on the medullary chemoreceptor trigger zone, contributing to its antiemetic efficacy. This combined mechanism makes it particularly effective in the prevention and treatment of motion sickness and vertigo. Meclizine is commonly prescribed for balance disorders such as Ménière’s disease and other conditions affecting the inner ear.
Meclizine, marketed under brand names such as Bonine, is administered orally and is well known for its relatively long duration of action. Therapeutic effects generally begin within one hour of administration and may last for up to 24 hours. Compared with other first-generation antihistamines, meclizine produces less sedation, making it suitable for both preventive and symptomatic management of motion-related nausea and dizziness.
Meclizine Hydrochloride — third party manufacturing & bulk supply
Meclizine Hydrochloride 12.5 mg, 25 mg, 50 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Indicative minimum order quantity
Meclizine Hydrochloride is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Meclizine Hydrochloride listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Meclizine Hydrochloride →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Meclizine Hydrochloride is used for the prevention and treatment of motion sickness and for the relief of nausea, vomiting, and dizziness associated with vestibular disorders such as vertigo and Ménière’s disease. It helps reduce balance-related symptoms by suppressing vestibular stimulation.
Meclizine Hydrochloride is a synthetic piperazine-derived antihistamine formulated as the hydrochloride salt to improve stability and oral absorption.
Meclizine Hydrochloride is marketed under trade names such as Antivert and Bonine in the United States and as Meclozine or Meclozine Hydrochloride in EU and UK markets.
Meclizine Hydrochloride is manufactured by multiple pharmaceutical companies worldwide, including originator and generic manufacturers supplying regulated and non-regulated markets.
Common brand names include Antivert, Bonine, and Meclozine.
Meclizine Hydrochloride is manufactured in several countries, including the USA, India, and various EU nations, by GMP-compliant pharmaceutical manufacturers.
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