Trihexiphenidyl Hydrochlorid Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 2mg

Reference Brands: Artane (USA/EU/India), Parkin (india/LATAM)

Category: Antipsychotropic Drugs

Trihexyphenidyl is used alone or together with other medicines (e.g., levodopa) to treat Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced.

Product Description:

Trihexyphenidyl is an anticholinergic medication widely used to manage the motor symptoms associated with Parkinson’s disease, including tremors, muscle stiffness, spasms, and poor muscle control. It works by blocking the neurotransmitter acetylcholine in the central nervous system, helping restore the balance between acetylcholine and dopamine, which improves voluntary muscle movement and reduces involuntary motor symptoms.

Approved by the FDA in June 2003 for idiopathic, postencephalitic, and arteriosclerotic Parkinsonism, Trihexyphenidyl is also effective in treating movement disorders caused by certain central nervous system (CNS) medications such as fluphenazine, haloperidol, and chlorpromazine. It is typically administered orally in tablet form, with dosage tailored to the severity of symptoms and patient tolerance.

Trihexyphenidyl’s use requires careful monitoring due to potential side effects including dry mouth, blurred vision, constipation, urinary retention, and cognitive impairment. It is contraindicated in patients with narrow-angle glaucoma, gastrointestinal obstruction, or certain cardiovascular conditions. Proper dosing and regular follow-up are essential to minimize toxicity and optimize therapeutic outcomes, making it a critical tool for healthcare professionals managing Parkinsonian and drug-induced extrapyramidal symptoms.