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Tramadol Hydrochloride Extended-Release Tablets bulk supplier for pharma manufacturers

Tramadol Hydrochloride Extended-Release Tablets 100 mg, 200 mg, 300 mg Suppliers & Bulk Manufacturers

Available Forms: Extended-Release Tablets

Available Strengths: 100 mg, 200 mg, 300 mg

Reference Brands: Ultram(US); Tramacet, Ultracet(EU)

Category: Analgesic

Tramadol Hydrochloride ER inhibits reuptake of serotonin and norepinephrine while activating opioid receptors, reducing pain signals centrally. Benefits include sustained pain relief for moderate to severe pain, improved mobility, and long-lasting analgesia. It offers rapid onset, fewer gastrointestinal side effects, and suitability for chronic pain management when used under supervision.

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Product Description:

OpenAI GPT-4o mini Tramadol Hydrochloride ER (Extended-Release) tablets are approved in the US and EU for moderate to severe pain management. In the US, brands like Ryzolt and ConZip are regulated by the FDA, supported by extensive clinical data, and controlled due to dependence risk. In the EU, EMA-regulated products such as Twynsta and generics require comprehensive dossiers demonstrating safety, efficacy, and manufacturing standards. Both regions enforce strict control measures, label warnings, and pharmacovigilance programs for ongoing safety monitoring. We support efficient market access, ensuring adherence to European and American standards for safe, effective pain therapy.

Controlled medicine — licensed supply only

This product is controlled in many countries under narcotic, psychotropic, precursor or other drug laws, which vary by country. We supply only licensed buyers holding any import certificate, permit or authorisation their national authority requires, and the Indian manufacturer or exporter must hold the required licences. In India, each export of a narcotic drug or psychotropic substance needs an export authorisation, and export of ephedrine, pseudoephedrine or their preparations a No Objection Certificate, from the Narcotics Commissioner (Central Bureau of Narcotics). We verify permits before quoting.

Tramadol Hydrochloride Extended-Release Tablets — third party manufacturing & bulk supply

Tramadol Hydrochloride Extended-Release Tablets 100 mg, 200 mg, 300 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Tramadol Hydrochloride Extended-Release Tablets is supplied as Extended-Release Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Tramadol Hydrochloride Extended-Release Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Tramadol Hydrochloride is used for the management of moderate to moderately severe pain. It works as an opioid analgesic by acting on the central nervous system to reduce the perception of pain.

It is made from tramadol hydrochloride, a synthetic opioid derived through chemical synthesis, designed to provide effective pain relief.

Common trade names include Ultram ER, ConZip, and Rybix ODT.

Ultram ER and Rybix ODT have been marketed by Johnson & Johnson / Janssen Pharmaceuticals, while ConZip is produced by Cypress Pharmaceuticals. Many manufacturers worldwide also produce generic tramadol hydrochloride.

The generic name is tramadol hydrochloride.

Well-known brand names include Ultram ER, ConZip, and Rybix ODT.

Tramadol Hydrochloride is manufactured in multiple countries including India, the USA, and several EU regions by various branded and generic pharmaceutical manufacturers.

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