Tiopronin 100 mg, 200 mg , 300 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets, Capsules

Available Strengths: 100 mg, 200 mg , 300 mg

Reference Brands: Thiola (USA), Mercaptamine (EU)

Category: Nephrology

Tiopronin is a Nephrology product available as Tablets, Capsules in strengths 100 mg, 200 mg , 300 mg. It corresponds to the reference brands Thiola (USA), Mercaptamine (EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Tiopronin, marketed under the brand name Thiola, is a medication used to manage cystinuria, a rare genetic disorder that causes excessive cystine in the urine and leads to recurrent kidney stone formation. Tiopronin works by binding to cystine, forming a more soluble complex that reduces the risk of cystine crystallization and stone formation, helping to prevent kidney damage and associated complications.

The medication is indicated for patients weighing 20 kilograms (44 lb) and above with severe homozygous cystinuria who do not respond adequately to standard measures such as high fluid intake, urinary alkalinization, and dietary modifications. Tiopronin is used as part of a comprehensive treatment plan to control cystine excretion and maintain kidney function.

Administered orally, Tiopronin requires careful monitoring to ensure efficacy and safety. Side effects may include gastrointestinal disturbances, rash, or changes in liver function, making regular follow-up and laboratory testing important. By effectively reducing cystine precipitation, Tiopronin provides a valuable therapeutic option for patients with severe cystinuria, helping to decrease the frequency of kidney stone formation, improve quality of life, and support long-term renal health.