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Atrasentan Hydrochloride bulk supplier for pharma manufacturers

Atrasentan Hydrochloride Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 0.75 mg, 1.25 mg, 10 mg

Reference Brands: Xinlay (USA/EU), Vanrafia (USA/LATAM)

Category: Nephrology

Atrasentan Hydrochloride is available in Tablets and strengths such as 0.75 mg, 1.25 mg, 10 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Atrasentan Hydrochloride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Atrasentan Hydrochloride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Atrasentan hydrochloride is an oral medication used to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgA nephropathy) who are at risk of rapid disease progression. IgA nephropathy is a chronic kidney disorder characterized by the buildup of immunoglobulin A (IgA) in the kidneys, leading to inflammation and gradual damage to kidney tissues. One of the key indicators of disease progression in these patients is elevated protein levels in the urine, commonly measured by the urine protein-to-creatinine ratio.

Atrasentan belongs to a class of medicines known as endothelin receptor antagonists. It works by selectively blocking endothelin-A receptors, which play a significant role in kidney inflammation, fibrosis, and increased protein leakage through the kidneys. By inhibiting this pathway, atrasentan helps reduce proteinuria and may contribute to slowing the progression of kidney damage in patients with IgA nephropathy.

The medicine is taken orally and is generally prescribed as part of a comprehensive treatment plan that may include supportive kidney care and monitoring by healthcare professionals. Atrasentan represents an important targeted therapy option for patients with progressive kidney disease, helping manage proteinuria and supporting long-term kidney health outcomes.

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Frequently Asked Questions

Atrasentan hydrochloride has been investigated for the treatment of diabetic kidney disease (diabetic nephropathy) and previously studied in certain cancers such as prostate cancer. It works by targeting endothelin receptors that play a role in inflammation, fibrosis, and kidney damage.

Atrasentan hydrochloride is a synthetic small-molecule endothelin-A receptor antagonist developed to selectively block endothelin signaling, which contributes to kidney disease progression and vascular complications.

A known trade or development name associated with atrasentan hydrochloride is Xinlay, primarily used during clinical development.

Atrasentan hydrochloride was originally developed and studied by AbbVie (formerly Abbott Laboratories) as part of its research programs in oncology and kidney disease.

The generic name of Xinlay is atrasentan hydrochloride.

A commonly referenced brand or development name for atrasentan hydrochloride is Xinlay.

Atrasentan hydrochloride for clinical and research use is produced in GMP-certified pharmaceutical manufacturing facilities associated with global pharmaceutical companies and approved contract manufacturers.

Yes, Atrasentan Hydrochloride is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Atrasentan Hydrochloride is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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