Ritonavir & Lopinavir Tablets bulk supplier for pharma manufacturers

Ritonavir & Lopinavir Tablets 50mg + 200 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 50mg + 200 mg

Reference Brands: Kaletra (USA/EU)

Lopinavir 200 mg with ritonavir 50 mg heat-stable tablets, a boosted HIV protease inhibitor combination for adults and children, for importers, distributors, hospitals and HIV programme buyers.

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Product Description:

These film-coated tablets contain lopinavir 200 mg with ritonavir 50 mg. Lopinavir is the HIV protease inhibitor that does the antiviral work, blocking the enzyme the virus needs to make mature, infectious particles. Ritonavir is a low-dose booster: it inhibits CYP3A4, which would otherwise clear lopinavir quickly, so levels stay high enough for twice-daily dosing. This heat-stable tablet replaced earlier soft capsules that needed refrigeration. A 100 mg/25 mg paediatric tablet and an oral solution are separate products.

It is used with other antiretrovirals for HIV-1 infection in adults and children, and has been widely used in second-line regimens. Adults usually take two tablets twice daily, swallowed whole with or without food, as crushing lowers absorption. Diarrhoea, nausea and raised lipids are common; pancreatitis and PR or QT prolongation are possible. Interactions are numerous: simvastatin, lovastatin and oral midazolam are contraindicated, rifampicin lowers lopinavir levels and is not co-administered, and hormonal contraceptives may fail.

Sourcing notes. The combination is on the WHO Model List of Essential Medicines, and HIV programme tenders often ask for WHO prequalification or approval by a stringent regulator. The tablets need no cold chain but stay in the original container at room temperature; bottles of 120 tablets are a common adult pack. Expect a CTD or ACTD dossier with bioequivalence data and zone IVb stability for hot humid markets. Ask for a CoA per batch with assay and dissolution for both actives, the GMP certificate and a CoPP. It is prescription-only. Say whether paediatric presentations are needed too.

Ritonavir & Lopinavir Tablets — third party manufacturing & bulk supply

Ritonavir & Lopinavir Tablets 50mg + 200 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Ritonavir & Lopinavir Tablets is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Ritonavir & Lopinavir Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Ritonavir & Lopinavir is used for the treatment of HIV-1 infection. The combination helps reduce viral load, improve immune function, and slow the progression of HIV. It is commonly used as part of antiretroviral therapy under the supervision of an HIV specialist.

This medicine is made from two protease inhibitors: Lopinavir, which blocks the action of HIV protease enzymes, and Ritonavir, which boosts the level and effectiveness of Lopinavir by slowing its metabolism in the body.

The most widely known trade name for this combination is Kaletra.

Kaletra is originally manufactured by AbbVie. Several pharmaceutical companies also produce licensed or generic versions in various countries.

The generic name is Lopinavir and Ritonavir.

The primary brand name is Kaletra, while multiple generic brand names are available depending on the manufacturer and region.

It is manufactured in several regions, including the United States and Europe by AbbVie, and in India by various approved manufacturers producing generic versions.