Pirfenidone Capsule 267 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 267 mg

Reference Brands: Esbriet (USA/EU)

Category: Respiratory Disorder

Pirfenidone 267 mg hard capsules, an oral antifibrotic for idiopathic pulmonary fibrosis. Listed for importers, distributors and hospital pharmacies sourcing specialist respiratory medicines.

Product Description:

Pirfenidone is an oral antifibrotic medicine. Its exact mechanism is not fully known, but it reduces fibroblast growth and the production of collagen and of growth factors such as TGF-beta that drive scarring, and it has anti-inflammatory effects. This page lists 267 mg hard capsules. The capsule was the first form of pirfenidone, and its low unit strength allows a gradual start. Film-coated tablets of 267 mg and 801 mg also exist; the 801 mg tablet replaces three capsules at full dose.

Pirfenidone is used for idiopathic pulmonary fibrosis in adults, where it slows the decline in lung function. Treatment starts at one capsule three times a day and rises over two weeks to three capsules three times a day, 2,403 mg daily, taken with food to limit nausea and dizziness. Photosensitivity and rash are common, so patients avoid strong sun and use high-factor sunscreen. Liver tests are checked before and during treatment. Fluvoxamine is contraindicated, and smoking speeds metabolism and reduces exposure.

Sourcing notes. Pirfenidone is a prescription-only specialist medicine, dispensed mainly through respiratory clinics and hospital pharmacies. Capsules come in bottles or blisters, and packs are often sized separately for titration and maintenance, so state which you need. Ask for a CTD or ACTD dossier, bioequivalence data against the reference capsule and zone IVb stability data for tropical markets. Storage follows the labelled room-temperature condition. Each batch should come with a CoA, plus the GMP certificate and a CoPP. In your enquiry, state pack format, shelf life at delivery and target country.