Pazopanib 200mg, 400mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 200mg, 400mg
Reference Brands: Votrient
Category: Oncology Cancer Care
Pazopanib is a tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma (kidney cancer) and soft tissue sarcoma. It works by inhibiting multiple tyrosine kinases involved in tumor growth and angiogenesis (the formation of new blood vessels), thereby slowing or stopping the progression of cancer.
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Product Description:
Pazopanib inhibits VEGF receptors one to three, PDGFR-alpha and beta, and KIT, cutting off the blood supply a solid tumour needs to grow beyond a few millimetres. Its position among the antiangiogenic kinase inhibitors rests less on superior potency than on tolerability: in a direct comparison in kidney cancer against sunitinib it showed similar efficacy with a different and, to most patients, preferable side effect profile, particularly less fatigue and hand-foot syndrome.
It is used for advanced renal cell carcinoma and for advanced soft tissue sarcoma after prior chemotherapy, taken once daily on an empty stomach — food substantially increases absorption and risks overdose. Hepatotoxicity is the defining safety issue and carries a boxed warning, with liver function monitored before treatment and repeatedly during the first months. Hypertension, diarrhoea, hair colour change, QT prolongation, haemorrhage and impaired wound healing occur; treatment is stopped before surgery.
Sourcing notes. Originator in most markets, with generic entry in some — confirm per destination. Two tablet strengths support dose reduction, which is frequent. Liver function monitoring capability at the destination is a practical prerequisite. Oral solid, room temperature.
Pazopanib — third party manufacturing & bulk supply
Pazopanib 200mg, 400mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Pazopanib is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Pazopanib listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
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