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Cabozantinib bulk supplier for pharma manufacturers

Cabozantinib Suppliers & Bulk Manufacturers

Available Forms: Tablets / Capsules

Available Strengths: 20 mg, 40 mg, 60 mg, 80mg, 100mg

Reference Brands: Cometriq (USA), Cabometyx (USA/EU)

Category: Oncology Cancer Care

Cabozantinib is an oral tyrosine kinase inhibitor that targets multiple receptors involved in tumor growth, angiogenesis, and metastasis. It is used in the treatment of advanced cancers, including renal cell carcinoma (RCC), hepatocellular carcinoma (HCC), medullary thyroid cancer (MTC), differentiated thyroid cancer (DTC), and neuroendocrine tumors (NETs). Cabozantinib helps slow tumor progression and improve patient outcomes by inhibiting pathways critical for cancer cell survival and proliferation.

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Product Description:

Cabozantinib inhibits several receptor tyrosine kinases at once, most importantly MET, VEGFR2 and AXL. That combination is deliberate: blocking VEGF alone starves a tumour of blood supply but also drives up MET and AXL signalling, which promotes invasion and metastasis — so inhibiting all three simultaneously attacks both the vasculature and the escape route.

It is used for advanced renal cell carcinoma, hepatocellular carcinoma after sorafenib, medullary thyroid cancer, and differentiated thyroid cancer refractory to radioactive iodine, alone or with immune checkpoint inhibitors. Adverse effects are substantial and dose reduction is common: diarrhoea, hand-foot skin reaction, hypertension, fatigue, weight loss and stomatitis. Serious risks include haemorrhage, gastrointestinal perforation and fistula, and impaired wound healing, so treatment is stopped before surgery.

Sourcing notes. Two formulations exist — capsules and tablets — with different strengths and different approved indications, and they are NOT interchangeable milligram for milligram. Confusing them is a documented error. Any quotation must state which, together with the pack size. Originator product in most territories, with patent position and any settlement-dated generic entry varying by market, so supply routes must be confirmed per destination before commitment. Oral solid handling, no cold chain, but controlled distribution in several markets.

Cabozantinib — third party manufacturing & bulk supply

Cabozantinib is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Cabozantinib is supplied as Tablets / Capsules — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Cabozantinib listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Cabozantinib is listed as Tablets / Capsules in 20 mg, 40 mg, 60 mg, 80mg, 100mg. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Cabozantinib is referenced against Cometriq (USA), Cabometyx (USA/EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.

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