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Methadone oral solution bulk supplier for pharma manufacturers

Methadone Oral Solution 1 mg/mL, 10 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Oral Solution

Available Strengths: 1 mg/mL, 10 mg/mL

Reference Brands: Generic formulations marketed under different names

Category: Addiction Medicine / Substance Use

Methadone Oral Solution is a Addiction Medicine / Substance Use product available as Oral Solution in strengths 1 mg/mL, 10 mg/mL. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Methadone (complete generic name: methadone hydrochloride) is a potent synthetic opioid medication widely used in modern medicine for the management of opioid dependence and chronic pain. It acts as a long-acting opioid agonist that works on the same receptors in the brain as other opioids, helping to reduce withdrawal symptoms and cravings in individuals with opioid use disorder. Because of its long duration of action, methadone is commonly used in opioid substitution therapy programs under medical supervision.

In addition to addiction treatment, methadone hydrochloride is also prescribed for the management of moderate to severe chronic pain, particularly when other analgesics are not effective or suitable. The medicine is most often administered orally in the form of tablets or oral solution, which allows controlled and consistent dosing for patients undergoing long-term therapy. In clinical settings, treatment plans may vary depending on the patient’s condition, ranging from short-term withdrawal management to long-term maintenance therapy.

Due to its potency and long-acting effects, methadone must be used strictly under medical guidance and according to regulatory requirements. Proper dosing, monitoring, and professional supervision are important to ensure safe and effective treatment outcomes for patients receiving methadone therapy.

Methadone Oral Solution — third party manufacturing & bulk supply

Methadone Oral Solution 1 mg/mL, 10 mg/mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Methadone Oral Solution listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Methadone hydrochloride oral solution is used primarily for the treatment of opioid use disorder (opioid dependence) as part of opioid substitution therapy programs. It helps reduce withdrawal symptoms and cravings in people who are dependent on opioids such as heroin or morphine. In some cases, it may also be prescribed for the management of severe chronic pain when other pain treatments are not effective.

Methadone oral solution is made from the active pharmaceutical ingredient methadone hydrochloride, which is a synthetic opioid agonist that acts on opioid receptors in the brain. The formulation also includes excipients such as purified water, stabilizers, flavoring agents, and preservatives depending on the manufacturer.

Common trade names for methadone hydrochloride oral solution include Methadose, Physeptone, and Methadone Martindale Pharma, along with several approved generic methadone oral solutions in different countries.

Methadone oral solution is manufactured by multiple pharmaceutical companies globally, including Hikma Pharmaceuticals, Martindale Pharma (Ethical Medicines Industry Group suppliers in the UK), Molteni Farmaceutici in the EU, and various approved generic manufacturers in different regulated markets.

The generic name is methadone hydrochloride.

Examples of brand names include Methadose, Physeptone, Methadone Martindale Pharma, and other country-specific generic brand listings.

Methadone hydrochloride oral solution is manufactured in several countries including the United States, United Kingdom, Italy, and other EU and regulated pharmaceutical manufacturing hubs depending on the marketing authorization holder and supplier.

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