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Fomepizole bulk supplier for pharma manufacturers

Fomepizole 100 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 100 mg/mL

Reference Brands: Antizol (USA)

Category: Critical Care

Fomepizole is a Critical Care product available as Injection in strengths 100 mg/mL. It corresponds to the reference brand Antizol (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Fomepizole, also known as 4-methylpyrazole, is a critical care medication used primarily as an antidote for methanol and ethylene glycol poisoning. It is administered intravenously and can be used alone or in combination with hemodialysis in severe cases. Fomepizole works by inhibiting the enzyme alcohol dehydrogenase, which prevents the conversion of methanol and ethylene glycol into their highly toxic metabolites, formic acid and oxalic acid, respectively. By blocking this metabolic pathway, fomepizole significantly reduces the risk of metabolic acidosis, organ damage, and other life-threatening complications associated with toxic alcohol ingestion.

The effectiveness of fomepizole is highest when administered promptly after ingestion, as delayed treatment allows harmful metabolites to accumulate in the body. It is typically used under strict medical supervision in emergency and hospital settings. Fomepizole is considered the first-line therapy for toxic alcohol poisoning due to its safety profile, predictable pharmacokinetics, and efficacy in preventing further tissue damage. Regular monitoring of renal function, acid-base balance, and serum alcohol levels is recommended during therapy to ensure optimal outcomes.

Fomepizole — third party manufacturing & bulk supply

Fomepizole 100 mg/mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Fomepizole listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Fomepizole is used to treat toxic alcohol poisoning, including methanol and ethylene glycol ingestion, by preventing the formation of toxic metabolites.

Fomepizole is a synthetic chemical compound designed to inhibit the enzyme alcohol dehydrogenase and block the metabolism of toxic alcohols.

The trade name of fomepizole is Antizol.

Fomepizole is manufactured by multiple pharmaceutical companies worldwide, including the branded product Antizol.

The generic name is fomepizole.

The brand name is Antizol.

Fomepizole is manufactured in the USA, EU, and other countries by GMP-compliant manufacturers supplying hospitals and critical care centers.

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